kinase – Tripod Development

Charting chemical space

Posted on April 30, 2012April 22, 2013 by tripod

Charting, in a technical sense, is the process of mapping objects in high dimensional space to lower dimensional subspace, something which we have previously discussed using the FastMap algorithm. In ... Read More

The kinome navigator

Posted on April 13, 2011April 22, 2013 by tripod

In a recent paper, Metz et al. describe a statistical framework for constructing the kinome polypharmacology network. Using a large kinase panel (i.e., more than 150,000 activity values across 172 kin... Read More

The human kinome Java component

Posted on March 2, 2011February 19, 2013 by tripod

Update Feb. 2, 2013: This Java package is obsoleted; please checkout the latest code here. Recently, we received a request to be able to access to the human kinome dendrogram programmatically. We th... Read More

The human kinome (part 1)

Posted on December 30, 2010April 22, 2013 by tripod

Update Nov 27, 2012: The entire source code for this tool is available here. Kinases are an important class of enzymes that are therapeutically relevant for a wide range of indications such as cancer ... Read More

Tripod Development

Cheminformatics proving ground

Category: kinase

Charting chemical space

The kinome navigator

The human kinome Java component

The human kinome (part 1)