Skip to content
  • About
  • NPC
  • Inxight Drugs
  • GINAS
  • Tox21
  • CANVASS
  • Matrix
  • Pharos
  • Publications
  • Projects
  • Students

Tripod Development

Cheminformatics proving ground

Category: kinase

Charting chemical space

Charting chemical space

Posted on April 30, 2012April 22, 2013 by tripod
Charting, in a technical sense, is the process of mapping objects in high dimensional space to lower dimensional subspace, something which we have previously discussed using the FastMap algorithm. In ... Read More
The kinome navigator

The kinome navigator

Posted on April 13, 2011April 22, 2013 by tripod
In a recent paper, Metz et al. describe a statistical framework for constructing the kinome polypharmacology network. Using a large kinase panel (i.e., more than 150,000 activity values across 172 kin... Read More
The human kinome Java component

The human kinome Java component

Posted on March 2, 2011February 19, 2013 by tripod
Update Feb. 2, 2013: This Java package is obsoleted; please checkout the latest code here. Recently, we received a request to be able to access to the human kinome dendrogram programmatically.  We th... Read More
The human kinome (part 1)

The human kinome (part 1)

Posted on December 30, 2010April 22, 2013 by tripod
Update Nov 27, 2012: The entire source code for this tool is available here. Kinases are an important class of enzymes that are therapeutically relevant for a wide range of indications such as cancer ... Read More

Links

  • NCATS
  • NCATS on Bitbucket
  • NCATS on DockerHub
  • NCATS on GitHub
  • NCATS Public GitLab

Presentations

  • ACS Spring 2010
  • ACS Spring 2013
  • Chemaxon UGM 2008
  • Chemaxon UGM 2011
  • Chemaxon UGM 2012

Software

  • Automated R-group analysis
  • Fragment activity profiler
  • Kinome navigator
  • Kinome viewer
  • Library synthesizer
  • Molecular framework
  • MolPlot
  • MolSubspace
  • Multiple MCS
  • NCATSFind Firefox Addon
  • PubChem search server
  • Scaffold activity diagram
  • Scaffold hopper
  • Siphonify
  • Spectral hash code
  • Structure standardizer
  • Tautomer generator
  • The NPC browser
  • Tox21 chemical browser

Recent Posts

  • In Memoriam Samuel Aboagye
  • Informatics Post-Doctoral Fellow Position
  • Post-doctoral Position with the IDG Pharos Project
  • Post-doctoral Position in Combination Screening Informatics
  • In memoriam Eric Dawson

Recent Comments

  • Fingerprint Similarity Searches in MongoDB at So much to do, so little time on Large scale substructure searching
  • Accessing Chemistry on the Web Using Firefox at So much to do, so little time on NCATSFind: Resolving Chemical Content in Browser
  • Fingerprint Similarity Searches in MongoDB at So much to do, so little time on Large scale substructure searching
  • Wolf-D. Ihlenfeldt on NCATSFind: Resolving Chemical Content in Browser
  • Accessing Chemistry on the Web Using Firefox at So much to do, so little time on NCATSFind: Resolving Chemical Content in Browser

Meta

  • Log in
  • Entries RSS
  • Comments RSS
  • WordPress.org
  • About
  • NPC
  • Inxight Drugs
  • GINAS
  • Tox21
  • CANVASS
  • Matrix
  • Pharos
  • Publications
  • Projects
  • Students

HHS Vulnerability Disclosure
Theme Designed by InkHive.com. © 2022 Tripod Development. All Rights Reserved.