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Tripod Development

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Category: scaffold

Hopping for success

Hopping for success

Posted on April 17, 2013April 30, 2013 by tripod
Molecular scaffold is a fundamental concept in medicinal chemistry. Perhaps nowhere this is more apparent than during early stage discovery, where scaffolds are the primary means by which medicinal ch... Read More
The kinome navigator

The kinome navigator

Posted on April 13, 2011April 22, 2013 by tripod
In a recent paper, Metz et al. describe a statistical framework for constructing the kinome polypharmacology network. Using a large kinase panel (i.e., more than 150,000 activity values across 172 kin... Read More
Molecular framework

Molecular framework

Posted on August 25, 2010September 8, 2010 by tripod
Molecular framework forms the basis for which compounds are organized, indexed, and visualized within Tripod.  There are two types of framework currently being generated when compounds are registered... Read More

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