Serial ComboID mQC Cell Line X-axis Y-axis Median Excess Excess HSA Beta Gamma DBSumPos DBSumNeg Self Cross Response Matrix
1 1 good [1.00] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
BKM-120
PI3Kalpha Inhibitor
64.61 -571.87 1 0.92 1.53 -2.99 No
2 2 good [0.93] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Idelalisib
PI3Kdelta Inhibitor
54.62 -1,242.17 0.91 0.72 0.59 -3.3 No
3 3 good [0.94] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
MK-2206
AKT Inhibitor
73.01 -580.41 0.96 0.91 0.76 -3.86 No
4 4 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Dexamethasone
Antiinflammatory; glucocorticoid receptor antagonist
67 -1,155.76 0.9 0.78 1.89 -5.78 No
5 5 good [0.93] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Bardoxolone methyl
NF-kappaB signaling Inhibitor
65.03 -467.91 0.97 0.93 0.38 -2.71 No
6 6 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
SPC-839
IKK beta Inhibitor
68.13 -850.15 0.89 0.76 0.1 -4.01 No
7 7 good [1.00] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
PD-166285
cSRC Inhibitor
67.89 -346.59 0.99 0.93 1.05 -2.2 No
8 8 good [0.96] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
BEZ-235
mTOR Inhibitor
41.04 -767.66 1.02 0.79 2.95 -0.83 No
9 9 good [0.93] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Nintedanib
VEGFR-1/2/3 Inhibitor
61.59 -694.78 0.98 0.85 0.43 -3.01 No
10 10 good [1.00] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Pictilisib
PI3K Inhibitor
44.59 -526.62 1.1 0.88 1.78 -0.86 No
11 11 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Everolimus
mTOR Inhibitor
39.01 -1,003.01 1.01 0.74 1.69 -0.44 No
12 12 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Doxorubicin
DNA Topoisomerase II Inhibitor
59.02 -485.32 1.08 0.89 0.88 -1.82 No
13 13 good [0.99] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
KU-0060648
DNA-PK Inhibitor
61.59 -948.44 0.92 0.8 0.32 -3.56 No
14 14 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
GDC-0980
mTOR Inhibitor
61.8 -692.39 0.96 0.89 1.08 -3.34 No
15 15 good [0.98] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Flavopiridol
CDK1/2/4/6/7/9 Inhibitor
54.08 -316.71 1.07 0.96 1.83 -0.94 No
16 16 good [0.99] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Withaferin A
NF-kappaB Activation Inhibitor
74.27 -529.58 0.93 0.91 0.76 -4.39 No
17 17 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
AZD-7762
Chk1/2 Inhibitor
66.55 -490.52 1 0.94 0.88 -2.69 No
18 18 good [0.96] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Plinabulin
Tubulin polymerization Inhibitor
56.14 -297.07 1.02 0.96 0.74 -2.1 No
19 19 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Dasatinib
Bcr-Abl Inhibitor
62.95 -420.76 1 0.96 0.89 -2.64 No
20 20 good [0.97] TMD8 Ibrutinib (PCI-32765)
BTK Inhibitor
Podofilox
Antimitotic Agent
74.34 -206.79 0.99 0.98 0.96 -2.39 No